Authority for technical supervision of works in the Republic of Moldova has been established on 15 September 1945. Under Decision of People's Commissars Council no 850 of 15.09.1945 the State Mining and Technical Inspectorate within the People's Commissars Council of the Soviet Socialist Republic of Moldova has been created. The purpose of Inspectorate was to exercise control over the safe activities at mining and industrial objects.

Under Decision of Ministries Council of the SSRM no 353 of 22 August 1958 the State Inspectorate on Supervision on Safe industry works and Mining Supervision within the Ministries Council of the SSRM has been established. This Inspectorate included the State Inspectorate on Boilers and Elevators and the Technical Gas Supervision authorities.

In 1968 State Inspectorate was transformed in the Department on Supervision on Safe industry works and Mining Supervision within the Ministries Council of the SSRM (state mining and technical supervision).

In February 1982 the Department on Supervision on Safe industry works and Mining Supervision was transformed in the State Council on Supervision on Safe industry works and Mining Supervision.

In July 1990 the State Council was transformed in the State Inspectorate on Supervision of Safe Works.

In March 1991 the State Inspectorate was transformed in the State Technical Supervision Department.

In September 1992 the State Standards, Metrology and Technical Department, as a result of merger of the State Technical Supervision Department and the State Standards and Metrology Department has been created.

In October 1994 the State Department was transformed in the Standards, Metrology and Technical Supervision Department (SMTSD).

In June 1996 within the Department the State Enterprise "Center for Technical Expertise" has been established, followed by its transformation, in November 1998, in the State Enterprise "National Agency for Technical Supervision" (NATS), which included the following entities: Boiler and Elevators Inspectorate, Technical Supervision Inspectorate for Gas, Chemical and Technological Inspectorate, Mining and Technical Inspectorate, Radioactive Protection Inspectorate, Balti, Cahul, Ceadir-Lunga subdivisions of the Technical Supervision Agency, Certification Department, Human Resources Attestation Bureau, Testing laboratory, Petroleum Quality Control Inspectorate. At that time, technical supervision in the Republic of Moldova, as was provided by the Resolution of the Government no 776 of 25 October 1994, was focused on the state regulation and supervision of mining works and geological works and subsoil protection; storage and use of explosives and toxic substances, exploitation of explosive objects; safe use and exploitation of elevators, boiler installations and pressure-based recipients; mining objects; gas pipelines and medium and low pressure pipelines design, construction and exploitation, as well as construction, use and absorption of the radioactive sources and wastes; storage of fuel and flammable substances; gas and fuel stations.

Until 1 March 2002 SMTSD was empowered to issue licenses to economic agents for the industrial safety-related activities. For the purposes of life and health safety of people, immovable and environmental protection and protection of the technology delivery, industrial dangerous assets-related services and installations, subject to the technical supervision, within the Dangerous Objects Certification Authority 9 certification bureaus (divided based on the types of products) have been functioning, in addition to the accredited laboratory for petroleum products and chemical reagents control. To this end, SMTSD, including through the State Enterprise "National Agency for Technical Supervision", at that time was performing works necessary to organization and improvement of efficiency of supervision activity and establishment of safe working conditions at industrial dangerous assets.

In 2005 pursuant to the Resolution of the Government no 586 of 16 June 2005, for the purposes of optimization and segregation of the competences related to the state supervision and control from the competences of rendering services in the area of conformity assessment, the State Enterprise "National Agency for Technical Supervision" has been transformed in the State Enterprise "Technical Centre for Industrial Safety and Certification" which was subordinated to the Ministry of Economy and Trade of the Republic of Moldova, in its quality of the entity subject to monitoring, as provided by the Resolution of the Government no 549 of 30.04.2008.

01.08.2018 - Reorganization of the State Enterprise "Technical Center for Industrial Safety and Certification" in the Limited Liability Company "Technical Center for Industrial Safety and Certification" has been completed